Links from sites with iffy link profiles?
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So the site http://www.cadenas.de/ appears to have good decent scores from the various Moz ranks, but when I check out the site in OSE there are a lot of really sketchy links that jump out, online pharmacy/drug type links. I should also add that the negative links are seemingly going to a weird blog deep in the site and only appear when I select all links to the root domain in OSE.
Everything about the site appears very legitimate except for the link profile which has me nervous. Would you guys pursue a link from this site?
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Depends on the price. If it's affordable enough to acquire the link, then yes, I'll go for it. It's just 1 link and it's a strong one for the mean time. You can then focus on other cleaner links after that.
I'm less scared when it comes to local tlds as well. They tend to get passed on.

My answer: I'll get the link.
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I personally would not. From what I have gathered about the latest Penguin update, it really targeted link neighborhoods. That is what you are describing when you are talking about the link profile of this other site.
Ask yourself this, does it look natural? Is there a relevancy from this site to mine? True it is just one link, but is it worth risking your link profiles integrity? My answer is always no.