Is there a best practice for using a general iso code for the EAME region and APAC region or should you break it out by country?

[GodfreyB2B]

I am creating a strategy for multiple regions and the US comes to market different than EAME (Europe, Africa, Middle East) and China. We were planning on using language and iso codes in subfolder's but the corporation only wants their content to be in German, English, and Queens English. Our current decision is to use /en-US/, /en/, /de/, /en-CN/, /zh-CN/. /en/ and /de/ will be what we use for EAME. This doesn't seem like the best idea as I think /en/ will get indexed as the US version and not the EAME version. Any suggestion or if clarification is needed is greatly appreciated.

[James-Distinction]

I don't think your proposed solution would present any problems.

However, we've only done this before by using /en-gb/ as the British English version (Queens English). This hasn't prevented the content being well indexed in countries that we would expect it to.

Remember that you can define Geotargeting within GWT for specific folders.

Also, Google recently introduced the rel="alternate" hreflang="x" meta tag which you might be able to use: https://support.google.com/webmasters/answer/189077

Hope that helps