Can being on to many directories cause a penalty from Google?

[PageOnePowerGang]

If a URL is on hundreds of different directories would that be enough for Google to penalize a website?

[KaneJamison]

Assuming that the directories are indeed low quality, I'd say that you probably wouldn't be penalized for it, they'd be more likely to just devalue those links. The odds might increase if you were overzealous with exact match anchor text in your links, but that would probably be more of an issue with anchor text than an issue with those specific directories.