Should I remove all rel=nofollow links?

[emerald]

I have a 60  page site that had some nofollow links sprinkled throughout, 50% of which are probably on its mailto: email links.

Should I remove all nofollows all in one go, or just the mailto links first, and later the others? Or has anyone had any negative effects in 2012 from this?

[AlanMosley]

No follow links leak link juice just like any other link, its just that link juice goes up in smoke instead of to the linked page, so there is no gain by having them, get rid of them and let the link juice flow.

The only valid reason to have a no-follow is when you are linking to a spammy site and you dont want google to think that you have anything to do with them.

[mytouchoftech]

If the links are pointed at your own sites, there's no reason not to let the juice flow to your own pages.